Budd-Chiari syndrome
ORPHA:131DiseaseMultigenic/multifactorialAll ages
Ассоциированные гены3
Фенотипы (HPO)23
Очень частый (80–99%)3
HP:0001409Portal hypertension
HP:0001541Ascites
HP:0001744Splenomegaly
Частый (30–79%)9
HP:0001394Cirrhosis
HP:0001945Fever
HP:0002027Abdominal pain
HP:0002040Esophageal varix
HP:0002240Hepatomegaly
HP:0002910Elevated circulating hepatic transaminase concentration
HP:0003155Elevated circulating alkaline phosphatase concentration
HP:0030243Hepatic vein thrombosis
HP:0033045Bipedal edema
Периодический (5–29%)11
HP:0000083Renal insufficiency
HP:0000952Jaundice
HP:0001082Cholecystitis
HP:0001824Weight loss
HP:0002024Malabsorption
HP:0002239Gastrointestinal hemorrhage
HP:0002480Hepatic encephalopathy
HP:0002586Peritonitis
HP:0005214Intestinal obstruction
HP:0005244Gastrointestinal infarctions
HP:0006554Acute hepatic failure
Эпидемиология12
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 1.5 | Europe | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.08 | Sweden | Value and class |
| Point prevalence | 1-9 / 1 000 000 | 0.14 | Sweden | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.05 | Denmark | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.02 | Japan | Value and class |
| Point prevalence | 1-9 / 1 000 000 | 0.24 | Japan | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.04 | France | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.21 | Italy | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.087 | Korea, Republic of | Value and class |
| Point prevalence | 1-9 / 1 000 000 | 0.529 | Korea, Republic of | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.1 | Worldwide | Value and class |
| Point prevalence | 1-9 / 100 000 | 1.1 | Worldwide | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)