Familial prostate cancer
ORPHA:1331DiseaseNot applicableAdult
Ассоциированные гены15
| Ген | Полное название | Тип связи | Тип гена | OMIM |
|---|---|---|---|---|
| CDH1 | cadherin 1 | Major susceptibility factor in | gene with protein product | 192090 |
| MSMB | microseminoprotein beta | Major susceptibility factor in | gene with protein product | 157145 |
| RAD51D | RAD51 paralog D | Biomarker tested in | gene with protein product | 602954 |
| ATM | ATM serine/threonine kinase | Major susceptibility factor in | gene with protein product | 607585 |
| SRD5A2 | steroid 5 alpha-reductase 2 | Candidate gene tested in | gene with protein product | 607306 |
| RNASEL | ribonuclease L | Major susceptibility factor in | gene with protein product | 180435 |
| BRCA1 | BRCA1 DNA repair associated | Major susceptibility factor in | gene with protein product | 113705 |
| BRCA2 | BRCA2 DNA repair associated | Major susceptibility factor in | gene with protein product | 600185 |
| CHEK2 | checkpoint kinase 2 | Major susceptibility factor in | gene with protein product | 604373 |
| ELAC2 | elaC ribonuclease Z 2 | Major susceptibility factor in | gene with protein product | 605367 |
| EPHB2 | EPH receptor B2 | Major susceptibility factor in | gene with protein product | 600997 |
| NBN | nibrin | Major susceptibility factor in | gene with protein product | 602667 |
| HNF1B | HNF1 homeobox B | Major susceptibility factor in | gene with protein product | 189907 |
| HOXB13 | homeobox B13 | Major susceptibility factor in | gene with protein product | 604607 |
| MSR1 | macrophage scavenger receptor 1 | Major susceptibility factor in | gene with protein product | 153622 |
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Annual incidence | 1-9 / 100 000 | 9.4 | United States | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)