Gliosarcoma
ORPHA:251576Histopathological subtypeNot applicableAdult
Ассоциированные гены12
| Ген | Полное название | Тип связи | Тип гена | OMIM |
|---|---|---|---|---|
| NFKBIA | NFKB inhibitor alpha | Biomarker tested in | gene with protein product | 164008 |
| MGMT | O-6-methylguanine-DNA methyltransferase | Biomarker tested in | gene with protein product | 156569 |
| EGFR | epidermal growth factor receptor | Part of a fusion gene in | gene with protein product | 131550 |
| FGFR1 | fibroblast growth factor receptor 1 | Part of a fusion gene in | gene with protein product | 136350 |
| FGFR3 | fibroblast growth factor receptor 3 | Part of a fusion gene in | gene with protein product | 134934 |
| TP53 | tumor protein p53 | Biomarker tested in | gene with protein product | 191170 |
| TACC3 | transforming acidic coiled-coil containing protein 3 | Part of a fusion gene in | gene with protein product | 605303 |
| TACC1 | transforming acidic coiled-coil containing protein 1 | Part of a fusion gene in | gene with protein product | 605301 |
| PPARG | peroxisome proliferator activated receptor gamma | Biomarker tested in | gene with protein product | 601487 |
| LZTR1 | leucine zipper like post translational regulator 1 | Disease-causing somatic mutation(s) in | gene with protein product | 600574 |
| SEPTIN14 | septin 14 | Part of a fusion gene in | gene with protein product | 612140 |
| IDH1 | isocitrate dehydrogenase (NADP(+)) 1 | Biomarker tested in | gene with protein product | 147700 |
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Annual incidence | <1 / 1 000 000 | 0.03 | Europe | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)