Preeclampsia
ORPHA:275555DiseaseNot applicableAdult
Ассоциированные гены3
| Ген | Полное название | Тип связи | Тип гена | OMIM |
|---|---|---|---|---|
| FLT1 | fms related receptor tyrosine kinase 1 | Major susceptibility factor in | gene with protein product | 165070 |
| STOX1 | storkhead box 1 | Major susceptibility factor in | gene with protein product | 609397 |
| CORIN | corin, serine peptidase | Major susceptibility factor in | gene with protein product | 605236 |
Фенотипы (HPO)27
Очень частый (80–99%)5
HP:0000093Proteinuria
HP:0000822Hypertension
HP:0004421Elevated systolic blood pressure
HP:0005117Elevated diastolic blood pressure
HP:0100767Abnormality of the placenta
Частый (30–79%)3
HP:0000083Renal insufficiency
HP:0100598Pulmonary edema
HP:0410019Epigastric pain
Периодический (5–29%)10
HP:0000077Abnormality of the kidney
HP:0000504Abnormality of vision
HP:0000707Abnormality of the nervous system
HP:0001511Intrauterine growth retardation
HP:0001518Small for gestational age
HP:0002027Abdominal pain
HP:0002315Headache
HP:0002910Elevated circulating hepatic transaminase concentration
HP:0006707Abnormality of the hepatic vasculature
HP:0031418Increased body mass index
Очень редкий (1–4%)9
HP:0001919Acute kidney injury
HP:0002360Sleep abnormality
HP:0002960Autoimmunity
HP:0003259Elevated circulating creatinine concentration
HP:0005202Helicobacter pylori infection
HP:0012622Chronic kidney disease
HP:0100651Type I diabetes mellitus
HP:0000147Polycystic ovaries
HP:0001873Thrombocytopenia
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 45 | Europe | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)