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Reactive arthritis

ORPHA:29207DiseaseMultigenic/multifactorial, Not applicableAdolescent, Adult, Elderly

Ассоциированные гены (2)

HLA-B
major histocompatibility complex, class I, B
Biomarker tested in
OMIM: 142830
HLA-B
major histocompatibility complex, class I, B
Major susceptibility factor in
OMIM: 142830

Фенотипы (36)

Очень частый (80–99%)15
HP:0000509Conjunctivitis
HP:0000962Hyperkeratosis
HP:0001369Arthritis
HP:0001386Joint swelling
HP:0001387Joint stiffness
HP:0001597Abnormality of the nail
HP:0002014Diarrhea
HP:0002754Osteomyelitis
HP:0002829Arthralgia
HP:0008391Dystrophic fingernails
HP:0011107Recurrent aphthous stomatitis
HP:0100543Cognitive impairment
HP:0100686Enthesitis
HP:0100773Cartilage destruction
HP:0200039Pustule
Частый (30–79%)6
HP:0000988Skin rash
HP:0001101Iritis
HP:0002027Abdominal pain
HP:0002037Inflammation of the large intestine
HP:0002103Abnormality of the pleura
HP:0003419Low back pain
Периодический (5–29%)15
HP:0500006Urethritis
HP:0000010Recurrent urinary tract infections
HP:0000554Uveitis
HP:0000613Photophobia
HP:0001659Aortic regurgitation
HP:0001701Pericarditis
HP:0001824Weight loss
HP:0001945Fever
HP:0002093Respiratory insufficiency
HP:0002206Pulmonary fibrosis
HP:0003565Elevated erythrocyte sedimentation rate
HP:0011227Elevated circulating C-reactive protein concentration
HP:0012219Erythema nodosum
HP:0012317Sacroiliac arthritis
HP:0034438Balanitis

Эпидемиология (1)

Point prevalence
1-9 / 100 000
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы