Immune thrombocytopenia
ORPHA:3002DiseaseNot applicableAll ages
Ассоциированные гены1
Фенотипы (HPO)20
Очень частый (80–99%)1
HP:0001873Thrombocytopenia
Частый (30–79%)11
HP:0000967Petechiae
HP:0000979Purpura
HP:0004420Arterial thrombosis
HP:0025329Anti-glutamic acid decarboxylase antibody positivity
HP:0025379Anti-thyroid peroxidase antibody positivity
HP:0030908Liver kidney microsome type 1 antibody positivity
HP:0032069Anti-thyroglobulin antibody positivity
HP:0034062Anti-insulin antibody positivity
HP:0034063Anti-islet antigen-2 antibody positivity
HP:4000170Anti-platelet antigen antibody positivity
HP:0034189Anti-thyroid-stimulating hormone receptor antibody positivity
Периодический (5–29%)6
HP:0000225Gingival bleeding
HP:0000421Epistaxis
HP:0000790Hematuria
HP:0000978Bruising susceptibility
HP:0002239Gastrointestinal hemorrhage
HP:0034263Abnormal vaginal bleeding
Очень редкий (1–4%)2
HP:0001342Cerebral hemorrhage
HP:0011885Hemorrhage of the eye
Эпидемиология7
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 25 | Europe | Value and class |
| Point prevalence | 1-9 / 100 000 | 9.5 | United States | Value and class |
| Annual incidence | 1-9 / 100 000 | 3.9 | United Kingdom | Value and class |
| Annual incidence | 1-9 / 100 000 | 6.75 | Europe | Value and class |
| Annual incidence | 1-9 / 100 000 | 2.68 | Denmark | Value and class |
| Point prevalence | 1-5 / 10 000 | 45 | Denmark | Value and class |
| Annual incidence | 1-9 / 100 000 | 2.9 | France | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)