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B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)

ORPHA:585909Etiological subtypeNot applicableAdolescent, Adult, Childhood, Elderly, Infancy

Ассоциированные гены (7)

CDKN2A
cyclin dependent kinase inhibitor 2A
Biomarker tested in
OMIM: 600160
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
Part of a fusion gene in
OMIM: 189980
BCR
BCR activator of RhoGEF and GTPase
Part of a fusion gene in
OMIM: 151410
IKZF1
IKAROS family zinc finger 1
Biomarker tested in
OMIM: 603023
TP53
tumor protein p53
Biomarker tested in
OMIM: 191170
FLT3
fms related receptor tyrosine kinase 3
Disease-causing somatic mutation(s) in
OMIM: 136351
HLA-C
major histocompatibility complex, class I, C
Major susceptibility factor in
OMIM: 142840

Эпидемиология (2)

Annual incidence
Unknown
Worldwide
Point prevalence
Unknown
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы