Alveolar rhabdomyosarcoma
ORPHA:99756Clinical subtypeMultigenic/multifactorial
Ассоциированные гены5
| Ген | Полное название | Тип связи | Тип гена | OMIM |
|---|---|---|---|---|
| FOXO1 | forkhead box O1 | Part of a fusion gene in | gene with protein product | 136533 |
| PAX3 | paired box 3 | Part of a fusion gene in | gene with protein product | 606597 |
| PAX7 | paired box 7 | Part of a fusion gene in | gene with protein product | 167410 |
| NF1 | neurofibromin 1 | Disease-causing somatic mutation(s) in | gene with protein product | 613113 |
| TP53 | tumor protein p53 | Disease-causing germline mutation(s) in | gene with protein product | 191170 |
Эпидемиология23
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Annual incidence | <1 / 1 000 000 | 0.018 | Austria | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.054 | Belgium | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.03 | Bulgaria | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.017 | Croatia | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.02 | Czech Republic | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.009 | Estonia | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.002 | Finland | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.033 | Germany | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.085 | Iceland | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.062 | Ireland | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.039 | Italy | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.005 | Latvia | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.021 | Lithuania | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.063 | Malta | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.035 | Norway | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.02 | Poland | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.02 | Portugal | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.029 | Slovakia | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.044 | Slovenia | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.027 | Spain | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.045 | Switzerland | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.036 | Netherlands | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.039 | United Kingdom | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)